CS-PEG decorated PLGA nano-prototype for delivery of bioactive ...
网页2017年9月1日 · These data are highly remarkable in cancer nano-targeting research. First, they suggest that PLGA-CS-PEG nanocomposites deliver a safe nano-approach to elevate the anti-tumor bioactivity of these compounds. Second, we have recognized a highly potent nano-platforms, namely PLGA-CS-PEG, for further tracking strategies in vivo models.
中科院理化所等在对抗铜绿假单胞菌生物膜感染领域获新进展 - 知乎
网页在体外铜绿假单胞菌生物膜中，采用8倍最小抑菌浓度（mic）时，cs-peg-lk13的抗菌效率可达72.70％，明显高于lk13肽（15.24%）和妥布霉素（33.57%）（图3）。 共聚焦激光扫描显微镜（CLSM）的成像显示，CS-PEG-LK13组装体可使生物膜中几乎所有细菌失活，而LK13肽和妥布霉 ...
Bio-orthogonally crosslinked catechol–chitosan hydrogel for effective ...
网页2022年4月1日 · A novel chitosan-poly (ethylene glycol)-hydrocaffeic acid (CS-PEG-HA) hybrid hydrogel was fabricated, with a four-fold improvement in the mechanical performance as compared to the pure chitosan hydrogel, while enhancing the mucoadhesiveness and hemostasis properties.
Biocompatible chitosan/polyethylene glycol/multi-walled carbon
网页2022年1月15日 · The performance of chitosan (CS)/polyethylene glycol (PEG) composite scaffolds could be optimized by introducing multi-walled CNTs (MWCNTs). CS/PEG/CNT composite scaffolds with CNT content of 1%, 3%, and 5% (1%=0.01 g/mL) were prepared by freeze-drying. Their physical and chemical properties and biocompatibility were evaluated.
PEG grafted chitosan scaffold for dual growth factor delivery for ...
网页2019年12月16日 · The goal of the study was to develop a Polyethylene glycol (PEG) cross-linked cotton-like chitosan scaffold (CS-PEG-H) by freeze-drying method and chemically conjugate heparin to the scaffold...
An ellagitannin-loaded CS-PEG decorated PLGA nano-prototype …
网页2023年4月17日 · Within the present study, PLGA-CS-PEG NPs were used to rapidly deliver, diminish clearance, and enhance the cancer-targeting ability of PNG and PN to cancer cells. Accordingly, PNG-PLGA-CS-PEG and PN-PLGA-CS …
Enzyme responsive GAG-based natural-synthetic hybrid hydrogel …
网页2016年5月1日 · We describe an enzymatically formed chondroitin sulfate (CS) and poly (ethylene glycol) (PEG) based hybrid hydrogel system, which by tuning the architecture and composition of modular building blocks, allows the application-specific tailoring of growth factor delivery and cellular responses.
A versatile pH sensitive chondroitin sulfate-PEG tissue
网页We developed a chondroitin sulfate-polyethylene glycol (CS-PEG) adhesive hydrogel with numerous potential biomedical applications. The carboxyl groups on chondroitin sulfate (CS) chains were functionalized with N-hydroxysuccinimide (NHS) to yield chondroitin sulfate succinimidyl succinate (CS-NHS).
CS-PEG decorated PLGA nano-prototype for delivery of bioactive …
网页To circumvent the low bioavailability and the short half-life time obstacles, we hypothesized a novel PLGA nano-platform functionalized with CS and PEG to encapsulate these phytochemicals. This encapsulation will protect the compounds from the phagocytic uptake and deliver PLGA-CS-PEG nano-prototype with high biodegradability and biosafety.
Tuning the surface functionality of polyethylene glycol-modified ...
网页2023年8月18日 · As seen in Fig. 3c, the thermogravimetric analysis (TGA) was used to explain the thermal stability of GO/CS, 1.5% PEG-GO/CS, and 2% PEG-GO/CS. The TGA is useful for analyzing a sample's...
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