GnRHa用法大盘点 原来用途那么多 - 丁香园 - DXY.cn
网页2016年4月29日 · GnRH-a 的应用. 1. 子宫内膜异位症. GnRH-a 持续用药可抑制雌二醇的分泌，从而抑制异位的子宫内膜组织的增殖。可用于巧克力囊肿或子宫腺肌病术后复发的预防，也可以用于子宫腺肌病的保守治疗，可使用 GnRH-a 使腺肌瘤缩小，为放置「曼月乐」创造条 …
Gonadotropin releasing-hormone analogs (GnRHa) - National …
网页2019年9月6日 · Gonadotropin releasing-hormone analogs (GnRHa) First synthesized in 1980, GnRHa desensitize and down-regulate GnRH-receptors, suppress gonadotropin secretion, and eventually reduce gonadal hormones to pre-pubertal levels (9,11,22,23).Basically, the native GnRH molecule is modified at least at the glycine 6 position, where it is substituted by another amino acid resulting in a super-agonistic ...
Gonadotropin-releasing hormone agonist - Wikipedia
网页A gonadotropin-releasing hormone agonist (GnRH agonist) is a type of medication which affects gonadotropins and sex hormones. [1] They are used for a variety of indications including in fertility medicine and to lower sex hormone levels in the treatment of hormone-sensitive cancers such as prostate cancer and breast cancer, certain gynecological disorders like heavy periods and endometriosis ...
一文读懂 GnRH-a 在辅助生殖中的 2 大常见应用 - 丁香园
网页2017年4月28日 · 2.GnRH-a 预处理在冻融胚胎移植中的价值 月经第二天长效 GnRH-a 1.8 mg，21 天后给予补佳乐（递增方案：3 mgbid*4 天，4 mgbid*4 天，5 mgbid*4-6 天；恒定方案：3-5 mg，bid*12-14 天），然后给予黄体支持 3 天后第四天早上给予冻融胚胎移植术。
关于闭经针GnRH-a，做一些科普 - 腾讯网
网页2024年1月16日 · 什么是GnRH-a？GnRH-a是一类药物的总称，中文比较绕口，翻译为“垂体促性腺激素激动剂”。这类药物包括诺雷德（戈舍瑞林）、达菲林（曲普瑞林）、抑那通（亮丙瑞林）、达必佳（曲普瑞林）和贝依（亮丙瑞林）等。尽管名字各异，但它们的作用机制相似：通过在脑垂体内抑制垂体分泌调节卵巢的 ...
姚书忠教授专访：GnRH-a是把双刃剑，降低副作用是关键
网页2018年6月25日 · GnRH-a是一种高选择性的卵巢促性腺激素受体的激动剂，其作用机制是与卵巢促性腺激素受体结合，抑制人体自身垂体促性腺激素的分泌，使卵巢处于静止状态，使得患者体内雌激素水平达到绝经期水平。. GnRH-a在妇科中的应用主要有两个方面：一方 …
Physiology, Gonadotropin-Releasing Hormone - StatPearls - NCBI Bookshelf
网页2023年5月1日 · Gonadotropin-releasing hormone (GnRH), a decapeptide, is a part of the hypothalamic-pituitary-gonadal axis, and being a part of this system makes it vital for human reproduction. Since its discovery by a group of Nobel laureate Andrew V. Schally in 1971 from porcine hypothalamus as one of the earliest hypothalamic releasing hormones, it has been a center of attention of research scientists ...
Gonadotropin releasing hormone agonists: Expanding vistas
网页Go to: Gonadotropin-releasing hormone (GnRH) agonists are derived from native GnRH by amino acid substitution which yields the agonist resistant to degradation and increases its half-life. The hypogonadotropic hypogonadal state produced by GnRH agonists has been often dubbed as “pseudomenopause” or “medical oophorectomy,” which are both ...
一文读懂 GnRH 拮抗剂在生殖技术中的应用 - 丁香园 - DXY.cn
网页2017年8月25日 · 除此之外，gnrh 激动剂联合 hcg，内源性 lh 和 hcg 类 lh 的「双重」作用，可能改善一部分患者单独应用 hcg 后卵成熟率低及子宫内膜容受性影响的问题。 gnrh 激动剂（gnrh-a）联合 hcg 具体方案：hcg (5000u) 联合 gnrh-a(0.2 mg) 诱发排卵 【2】 。 gnrh …
Gonadotropin-releasing hormone analogs: Mechanisms of …
网页The cellular mechanisms and action of the GnRH/GnRH receptor system have been clinically applied for the treatment of reproductive disorders and have widely been introduced in ART. New GnRH analogs, such as long-acting GnRH analogs and oral nonpeptide GnRH antagonists, are being continuously developed for clinical application.