Interleukin 6 - Wikipedia
网页Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. [5] In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation.
IL-6，至关重要的多功能细胞因子 - 知乎 - 知乎专栏
网页IL-6，至关重要的多功能细胞因子. 白介素6（interleukin 6，IL-6），是与炎症相关最为典型的细胞因子。. 它通过调节免疫和炎症反应，在宿主防御中发挥着重要作用。. 今天，小E就来和大家聊聊，IL-6的起源、特性、功能与应用。. 01. 发现过程. 上世纪70年代，IL-6 ...
白细胞介素-6 - 维基百科，自由的百科全书
网页白细胞介素-6 （Interleukin 6），简称 白介素-6 （IL-6，在人体内由 IL6 基因 编码 [5]），最初由日本免疫学家 岸本忠三 团队发现 [6]，是一种 介导 炎症 的 白细胞介素 （但在某些情况下也具有抗炎症作用） [7][5]。. 白细胞介素-6可由 T细胞 、 B细胞 、 单核细胞 ...
白细胞介素-6 - 百度百科
网页白介素-6是 趋化因子 家族的一种 细胞因子。. 1980年发现 成纤维细胞 经Poly I-C刺激后能产生一种抑制 病毒 复制的 细胞 因子，称为β2 干扰素 (IFN-β2)。. 以后的研究结果未能证实这种因子的直接 抗病毒 作用，但具有其它多方面的生物学功能，根据实验系统和功能 ...
炎症指标排头兵”--白介素6（IL-6）全面解读 - 知乎专栏
网页2024年3月1日 · CRP（C反应蛋白）、PCT（降钙素原）、IL-6（白介素-6）被誉为感染性疾病诊断的“新三大利器”，IL-6更是被称为“炎症指标排头兵”。. 炎症反应发生后，IL-6率先生成，产生后诱导CRP和PCT生成。. 研究显示，细菌感染后IL-6迅速升高，2小时达到高峰，其升 …
Interleukin-6: A Masterplayer in the Cytokine Network - PubMed
网页Interleukin-6 (IL-6) is a member of the pro-inflammatory cytokine family, induces the expression of a variety of proteins responsible for acute inflammation, and plays an important role in the proliferation and differentiation of cells in humans. IL-6 signaling is mediated by building a complex of I ….
IL-6 in Inflammation, Immunity, and Disease - PMC - National …
网页IL-6 in inflammation, immunity, and disease. IL-6 is a cytokine featuring pleiotropic activity; it induces synthesis of acute phase proteins such as CRP, serum amyloid A, fibrinogen, and hepcidin in hepatocytes, whereas it inhibits production of albumin.
IL-6 as a keystone cytokine in health and disease - Nature
网页2015年4月21日 · Here we review the complex biology associated with the IL-6 signaling cassette (i.e., the individual cytokine and receptor components that transduce IL-6 signals), its role in many infectious...
IL-6 in inflammation, autoimmunity and cancer - PMC
网页2020年12月18日 · IL-6 is involved both in immune responses and in inflammation, hematopoiesis, bone metabolism and embryonic development. IL-6 plays roles in chronic inflammation (closely related to chronic inflammatory diseases, autoimmune diseases and cancer) and even in the cytokine storm of corona virus disease 2019 (COVID-19).
Translating IL-6 biology into effective treatments - Nature
网页2020年4月23日 · IL-6 affects T cell and B cell differentiation and is the key driver of the acute-phase response in RA. Key symptoms and comorbidities such as pain, fatigue, anxiety, depression,...
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