Folinic acid - Wikipedia
网页Folinic acid, also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate and pyrimethamine. [2][3] It is also used in combination with 5-fluorouracil to treat colorectal cancer and pancreatic cancer, may be used to treat folate deficiency that results in anemia, and methanol poisoning. [3][4] It is taken by mout...
左亚叶酸钙(Levofolinate Calcium) - 药物靶点：TYMS_在研适应 …
网页别名. Calcium Levofolinate、Calcium levofolinate (INN)、Calcium Levofolinate Hydrate. + [9] 靶点. TYMS. 作用机制. TYMS抑制剂 (胸苷酸合成酶抑制剂)、DNA合成抑制剂. 治疗领域. 癌症 消化系统疾病 内分泌与代谢疾病. 在研适应症. 小肠癌 胰腺癌 结直肠癌 + [1] 非在研适应症. 结肠癌 药物中毒 粘膜炎 + [4] 原研机构. Pfizer Japan, Inc. 在研机构. Pfizer Japan, Inc. 江苏恒瑞医药股份有限公司. 非在研机构. Acrotech Biopharma LLC 初创企业 Wyeth AB …
注射用左亚叶酸钙详细说明书-注意事项-不良反应-用法用量-39药 …
网页【药品名称】 通用名称：注射用左亚叶酸钙. 英文名称：Calcium Levofolinate for Injection. 汉语拼音：Zhusheyong Zuoyayesuangai. 【成份】 本品主要成份为左亚叶酸钙，其化学名称为 (-)-N- [4 [ [ [ (6S)-2-氨基-5-甲酰基-1,4,5,6,7,8-六氢-4-氧代-6-蝶啶基]甲基]氨基]苯甲酰基]-L-谷氨酸钙盐五水合物。 其辅料为甘露醇。 【性状】 本品为类白色至黄色的疏松块状物或粉末。 【适应症】 与5-氟尿嘧啶合用，用于治疗胃癌和结直肠癌。 【用法用量】 左亚叶 …
Levoleucovorin: Uses, Interactions, Mechanism of Action
网页2016年5月19日 · Levoleucovorin is a folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal …
Folinic acid (leucovorin or calcium folinate) - Macmillan Cancer …
网页Folinic acid (also called calcium folinate or leucovorin) is not a chemotherapy drug. But it may be given with the chemotherapy drugs: fluorouracil (5FU) tegafur-uracil. methotrexate. Folinic acid is often given with 5FU to treat cancers of the colon, rectum and other parts of the digestive system. It makes 5FU work better.
Efficacy and safety of 5-fluorouracil (5-FU) / levofolinate ...
网页2021年1月22日 · Background: 5-fluorouracil (5-FU) / levofolinate / irinotecan (FOLFIRI) is one of the preferred regimens for patients (pts) with advanced pancreatic cancer (APC) who received prior gemcitabine-based therapy in the …
Levofolinic acid 50 mg/ml Solution for injection or infusion
网页2020年11月6日 · Biochemical rationale for the methotrexate rescue therapy with disodium levofolinate. Levofolinic acid is frequently used to diminish the toxicity and counteract the action of folate antagonists, such as methotrexate.
Calcium levofolinate | C20H23CaN7O7 | CID 137179783 - PubChem
网页Calcium levofolinate | C20H23CaN7O7 | CID 137179783 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Major innovations and clinical applications of disodium-levofolinate…
网页2019年6月4日 · The sodium salt of leucovorin-disodium levofolinate (Na-Lv) is a novel molecule with a pharmacological profile similar to Ca-FA. Owing to its higher solubility, it can be safely mixed with 5-FU in a single pump without the …
Calcium Levofolinate - Cerbios-Pharma SA - Reduced Folates
网页Calcium Levofolinate is used to reduce the toxic effects of some oncological therapies such as methotrexate and other medicines (Folic Acid antagonists). It is also prescribed to treat anaemia caused by folate deficiency and in synergistic combination with the chemotherapy agent 5-fluorouracil in treating colorectal cancer (FOLFOX or FOLFIRI ...