Lipopeptide - Wikipedia
网页A lipopeptide is a molecule consisting of a lipid connected to a peptide. [1] They are able to self-assemble into different structures. [1][2][3] Many bacteria produce these molecules as a part of their metabolism, especially those of the genus Bacillus, Pseudomonas and Streptomyces. [4]
Lipopeptide - an overview | ScienceDirect Topics
网页Lipopeptides and lipoproteins are the second largest group of biosurfactants. They are mainly obtained from bacteria (e.g., Bacillus and Pseudomonas genera) [15]. The lipopeptides are formed by a fatty acid (between C12 and C18) linked to a peptide chain (from 4 to 12 amino acids) [3,16].
Lipopeptides as tools in catalysis, supramolecular, materials ...
网页2023年9月19日 · Lipopeptides are amphiphilic peptides in which an aliphatic chain is attached to either the C or N terminus of peptides. Their self-assembly — into micelles, vesicles, nanotubes, fibres or...
Peptide hormones and lipopeptides: from self‐assembly to ...
网页2017年1月27日 · In therapeutic applications, the hydrophobic tail assists transport across the cell membrane, and the peptide epitope can then be used to target a specific cell via a ligand‐receptor complex 20. Lipopeptides are able to form supramolecular nanostructures such as fibrils, micelles and vesicles.
Lipopeptides as the Antifungal and Antibacterial Agents ...
网页2015年1月6日 · Synthetic lipopeptides are widely used as vaccine adjuvants to enhance immune response, but bacterial derived recombinant lipopeptide, such as Lipo-Nter, is a novel adjuvant that can be used to induce superior antitumor effects as compared to a synthetic lipopeptide .
A synthetic lipopeptide targeting top-priority multidrug ...
网页2022年3月25日 · Here the authors report the discovery and development of a synthetic lipopeptide with an improved safety and efficacy against top-priority MDR Gram-negative pathogens.
Lipopeptides: from self-assembly to bioactivity - Chemical ...
网页2015年3月18日 · Two main classes of lipopeptide are considered: (i) bacterially-expressed lipopeptides with a cyclic peptide headgroup and (ii) linear lipopeptides (with one or more lipid chains) based on bio-derived and bio-inspired amino acid sequences with current clinical applications.