Understanding the tumor immune microenvironment (TIME) for …
网页2018年4月23日 · The tumor immune microenvironment influences tumor progression and response to immunotherapy; its further characterization will improve therapeutic outcome.
Spatial single-cell protein landscape reveals vimentinhigh ... - Nature
网页3 天之前 · Tumor microenvironment heterogeneity in hepatocellular carcinoma (HCC) on a spatial single-cell resolution is unclear. Here, we conducted co-detection by indexing to profile the spatial ...
Microenvironment - an overview | ScienceDirect Topics
网页The cell microenvironment is the surrounding physical and biochemical condition of the cells, which directly or indirectly alter the physiological properties of the cells.
The updated landscape of tumor microenvironment and drug …
网页2020年8月25日 · Accumulating evidence shows that cellular and acellular components in tumor microenvironment (TME) can reprogram tumor initiation, growth, invasion, metastasis, and response to therapies.
The tumor microenvironment: Current Biology - Cell Press
网页2020年8月17日 · To overcome a hypoxic and acidic microenvironment, the tumor microenvironment coordinates a program that promotes angiogenesis to restore oxygen and nutrient supply and remove metabolic waste. Tumors become infiltrated with diverse adaptive and innate immune cells that can perform both pro- and anti- …
Understanding the microenvironment and how this controls cell …
网页2023年12月18日 · The microenvironment plays a critical role in influencing cell fate changes such as differentiation and fitness of tumor-infiltrated cells in HCC, leading to immune evasion. All the microenvironmental components work together to create a complex and dynamic ecosystem that influences HCC behavior and, importantly, therapeutic response and ...
Microenvironment drives cell state, plasticity, and drug response …
网页We identify a new intermediate co-expressor (IC) PDAC cell state, uncover distinct site- and subtype-specific TMEs, and demonstrate that TME signals are critical regulators of cancer cell state, plasticity, and response to therapy.
An overview of the tumor microenvironment, from cells to …
网页2020年11月26日 · There is a consensus according to which the understanding of the tumor microenvironment is important as a means to develop new approaches in the therapy of cancer. In this context, the present study is a review of the different types of non-malignant cells that can be found in tumors, with their pro or antitumoral actions, presence in tumors ...
Definition of microenvironment - NCI Dictionary of Cancer Terms
网页microenvironment. (MY-kroh-en-VY-run-ment) In biology, the cells, molecules, and structures (such as blood vessels) that surround and support other cells and tissues. Abnormal cells, such as cancer cells, can change their microenvironment. Changes in the microenvironment can affect how cancer cells grow and spread.
Engineered probiotic E.coli Nissle 1917 for release PTEN to
网页1 天前 · The cancer is one of the diseases of serious threat to people's health and life nowadays. But heterogeneity, drug resistance and treatment side effects of cancer, traditional treatments still have limitations. Tumor-targeting probiotics with a well-established Biosafety and efficient targeting as a delivery vectors to deliver anticancer genes or antitumor drugs to tumor microenvironment has ...
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