New Delhi metallo-beta-lactamase 1 - Wikipedia
网页NDM-1[1] is an enzyme that makes bacteria resistant to a broad range of beta-lactam antibiotics. These include the antibiotics of the carbapenem family, which are a mainstay for the treatment of antibiotic-resistant bacterial infections. The gene for NDM-1 is one member of a large gene family that encodes beta-lactamase enzymes called ...
NDM-1细菌 - 百度百科
网页NDM-1又名-“新德里金属－β－内酰胺酶1”，或者简称为NDM－1。. 据2010年8月11日出版的英国《柳叶刀－传染病》 期刊 介绍，有一种新出现的不明原因的病症正在一些国家流行，由于许多发病者曾在印度或巴基斯坦旅游和治疗，因而研究人员推测这种携带NDM-1的 ...
NDM-1 — A Cause for Worldwide Concern
网页2010年12月16日 · The most recent reports of superbugs in the professional and lay literature discuss NDM-1, which stands for New Delhi metallo-beta-lactamase 1 and actually refers not to a single bacterial...
NDM-1 (New Delhi metallo-beta-lactamase 1) - MedicineNet
网页2023年8月9日 · NDM-1 stands for a gene that produces New Delhi metallo-beta-lactamase in certain bacteria that cause infections. This is a substance that destroys the commonest types of antibiotics. Bacteria with the NDM-1 gene are part of a larger group of superbug bacteria that are extremely hard to treat and can spread easily in hospitals.
Superbug NDM-1: Characteristics, dangers, and solutions
网页2018年12月18日 · NDM-1 is a protein that certain bacteria produce. It makes them resistant to antibiotics, posing the potential threat of a superbug. While this poses a considerable threat to health, some ...
Enzyme Inhibitors: The Best Strategy to Tackle Superbug NDM-1 …
网页2021年12月24日 · The detailed generalization of crystal structure, enzyme activity center and catalytic mechanism, variants and global distribution, mechanism of action of existing inhibitors, and the development of scaffolds provides a reference for finding potential clinically effective NDM-1 inhibitors against drug-resistant bacteria.
NDM-1泛耐药肠杆菌科细菌 - 百度百科
网页NDM-1 (New Delhi metallo-β-lactamase 1, I型新德里金属卜内酰胺酶)泛耐药肠杆菌科细菌，对大多数抗菌药物包括β一内酰胺类、碳青霉烯类、氨基糖苷类、大环内酯类和喹诺酮类等抗菌药物具有广泛耐药性，仅对多勃菌素和替加环素敏感，给临床感染治疗带来很大困难 ...
The directed evolution of NDM-1 - PMC - National Center for ...
网页2023年10月24日 · One of the three most clinically relevant MBLs is New Delhi Metallo- β-Lactamase (NDM-1). The current study sought to investigate the in vitro protein evolution of NDM-1 β-lactamase using error-prone polymerase chain reaction.
The mechanism of NDM-1-catalyzed carbapenem hydrolysis is ... - Nature
网页2017年12月21日 · New Delhi metallo-β-lactamases (NDMs) hydrolyze almost all β-lactam antibiotics and pose a major public health threat. Here, the authors study the mechanism of NDM-1 catalyzed carbapenem ...
Potential inhibitors designed against NDM-1 type metallo-β
网页2017年8月23日 · NDM-1 has been identified as a new metalo-β-lactamase isolated from a Swedish patient who acquired urinary tract infection caused by Klebsiella pneumoniae 6. After the discovery of NDM-1, its...
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