Nitrofurantoin - StatPearls - NCBI Bookshelf
网页2023年5月29日 · Nitrofurantoin is an antibiotic medication that is used for the treatment of uncomplicated lower urinary tract infections. It is effective against most gram-positive and gram-negative organisms. Nitrofurantoin’s primary use has remained in treating and prophylaxis of urinary tract infections.
Nitrofurantoin: Uses, Interactions, Mechanism of Action
网页Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. 8, 9, 10 Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. 2 This drug is more resistant to the development of bacterial resistanc...
Nitrofurantoin - Wikipedia
网页Nitrofurantoin is an antibacterial medication of the nitrofuran class used to treat urinary tract infections, although it is not as effective for kidney infections. [ 10 ] . It is taken by mouth. [ 10 ] Common side effects include nausea, loss of appetite, diarrhea, and headaches. [ 10 ] .
Nitrofurantoin: Dosage, Mechanism/Onset of Action, Half-Life
网页2020年2月17日 · Mechanism of Action. Nitrofurantoin is reduced by bacterial flavoproteins to reactive intermediates that inactivate or alter bacterial ribosomal proteins leading to inhibition of protein synthesis, aerobic energy metabolism, DNA, RNA, and cell wall synthesis. Nitrofurantoin is bactericidal in urine at therapeutic doses.
Nitrofurantoin - Pharmaceutical Drugs - NCBI Bookshelf
网页Nitrofurantoin is used extensively in the treatment and prophylaxis of uncomplicated lower urinary-tract infections. The usual oral dose for adults is 50–100 mg four times daily, with meals and at bedtime. Treatment is usually continued for 14 days. The daily dose for children is 5–7 mg/kg given in four divided oral doses.
Nitrofurantoin: properties and potential in treatment of urinary …
网页2023年7月27日 · Nitrofurantoin (NF), a wide-spectrum antibiotic accessible since 1953, is utilized widely to treat urinary tract infections as it usually stays active against drug-resistant uropathogen.
Nitrofurantoin: mechanism of action and implications for …
网页Nitrofurantoin is an effective urinary tract antibacterial to which no clinically significant resistance development has occurred. We have previously shown that nitrofurantoin susceptibility in bacteria correlates with the presence of bacterial nitroreductases which convert nitrofurantoin to highly ….
Nitrofurantoin - PubMed
网页2023年5月29日 · Nitrofurantoin is an antibiotic medication that is used for the treatment of uncomplicated lower urinary tract infections. It is effective against most gram-positive and gram-negative organisms. Nitrofurantoin’s primary use has remained in treating and prophylaxis of urinary tract infections.
Nitrofurantoin revisited: a systematic review and meta-analysis of ...
网页2015年6月11日 · Nitrofurantoin's use has increased exponentially since recent guidelines repositioned it as first-line therapy for uncomplicated lower urinary tract infection (UTI). We conducted a systematic review and meta-analysis to assess nitrofurantoin's efficacy and toxicity in the treatment of lower UTI.
Nitrofurantoin - Nitrofurantoin - MSD Manual Professional Edition
网页Nitrofurantoin - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical Professional Version.