Osteolytic Lesions Due to Cancer - Verywell Health
网页2022年9月13日 · Osteolytic lesions, also called osteoclastic or lytic lesions, are areas of damaged bone that most often occur in people with certain cancers, such as multiple myeloma and breast cancer. On an X-ray, osteolytic lesions appear as tiny holes, giving the bone a "moth-eaten" or "punched-out" appearance.
Osteolysis (Bone Degeneration): Causes, Symptoms, Treatment
网页2019年10月28日 · What is osteolysis? Osteolysis is a progressive condition where bone tissue is destroyed. In this process, bones lose minerals (mostly calcium), softens, degenerates and become weaker. What causes osteolysis? Osteolysis occurs when cells in the bone called osteoclasts increase their activity and break down the surrounding minerals.
Osteolytic lesion - Wikipedia
网页An osteolytic lesion (from the Greek words for "bone" (ὀστέον), and "to unbind" (λύειν)) is a softened section of a patient's bone formed as a symptom of specific diseases, including breast cancer and multiple myeloma. This softened area appears as a hole on X-ray scans due to decreased bone density, although many other diseases are ...
Osteolytic bone lesion | Radiology Reference Article - Radiopaedia.org
网页2024年7月26日 · Osteolytic lesions, lytic or lucent bone lesions are descriptive terms for lesions that replace normal bone or with a vast proportion showing a lower density or attenuation than the normal cancellous bone. This comprises lesions with fatty liquid and solid soft tissue components.
Lytic Bone Lesions - StatPearls - NCBI Bookshelf
网页2022年10月22日 · Well-defined osteolytic bone tumors and tumor-like lesions have a plethora of differentials in different age groups. This activity reviews the etiology, presentation, evaluation, and management of lytic bone lesions and reviews the role of the interprofessional team in evaluating, diagnosing, and managing the condition.
Bone Metastases: An Overview - PMC - National Center for …
网页2017年3月3日 · Osteolytic, characterized by destruction of normal bone, present in multiple myeloma (MM), renal cell carcinoma, melanoma, non-small cell lung cancer, non-hodgkin lymphoma, thyroid cancer or langerhans-cell histiocytosis. The great majority of BC produces osteolytic metastases.
Lytic Bone Lesions From Multiple Myeloma - WebMD
网页2022年8月22日 · Also known as bone lesions or osteolytic lesions, lytic lesions are spots of bone damage that result from cancerous plasma cells building up in your bone marrow. Your bones can't break down and...
Mechanisms of osteolytic and osteoblastic skeletal lesions
网页2015年10月28日 · Osteolytic tumors, such as MM, disrupt the bone remodeling compartment, allowing exchange of soluble factors as well as direct cell-to-cell contact between MM cells and bone cells. Thus, physical exchange of cytokines and other factors between tumor cells and bone cells occurs and mediates the bone destruction and deficient bone formation ...
Molecular mechanisms and clinical management of cancer …
网页2020年7月29日 · The distant metastasis of cancer cells has long been known to have characteristic preferences. 1, 2 Bone is one of the most common metastatic sites for malignancies, such as breast, prostate, and...
Metastasis to bone: causes, consequences and therapeutic
网页2002年8月1日 · From this viewpoint, osteolytic metastases are believed to be caused by osteoclast-activating factors — the most important of which might be parathyroid-hormone-related peptide — and which are ...