Tanshinone - Wikipedia
网页Tanshinones are a class of chemical compounds. Examples include dihydrotanshinone, tanshinone I, or tanshinone IIA. These compounds are all naturally occurring and can all be isolated from Salvia miltiorrhiza. [1][2] Dihydrotanshinone I has been reported to have cytotoxicity to a variety of tumor cells. [3]
Tanshinones: Sources, Pharmacokinetics and Anti-Cancer Activities
网页2012年10月22日 · Tanshinones are a class of abietane diterpene compound isolated from Salvia miltiorrhiza (Danshen or Tanshen in Chinese), a well-known herb in Traditional Chinese Medicine (TCM). Since they were first identified in the 1930s, more than 40 lipophilic tanshinones and structurally related compounds have been isolated from Danshen.
Expansion within the CYP71D subfamily drives the ... - Nature
网页2021年1月29日 · Tanshinones are the bioactive nor -diterpenoid constituents of the Chinese medicinal herb Danshen (Salvia miltiorrhiza). These groups of chemicals have the characteristic furan D-ring, which...
Prospective therapeutic potential of Tanshinone IIA: An …
网页2021年2月1日 · Tanshinone IIA (Tan IIA) is a pharmacologically active lipophilic component of Salvia miltiorrhiza extract. Tan IIA shares a history of high repute in Traditional Chinese Medicine.
The Anticancer Properties of Tanshinones and the Pharmacological ...
网页2020年3月19日 · Tanshinone is a natural terpenoid and the main bioactive component isolated from traditional Chinese medicine Salvia miltiorrhiza. It is traditionally used in the treatment of cardiovascular and cerebrovascular diseases in China (Chen et al., 2012; Shi et al., 2019; Sun et al., 2019).
Pharmacological basis of tanshinone and new insights into tanshinone …
网页2020年10月1日 · The protective effect of tanshinone (0.1−10 μM) was shown to be related to the production of mitochondrial superoxide and enhanced mitochondrial SOD activity. Tanshinone can also significantly reduce intracellular NO and Ca 2+ levels.
Tanshinone IIA: A Review of its Anticancer Effects - PMC
网页2021年1月14日 · Tanshinone IIA (Tan IIA) is a pharmacologically lipophilic active constituent isolated from the roots and rhizomes of the Chinese medicinal herb Salvia miltiorrhiza Bunge (Danshen). Tan IIA is currently used in China and other neighboring countries to treat patients with cardiovascular system, …
Tanshinone I: Pharmacological activities, molecular mechanisms …
网页Tan I shows multiple therapeutic effects, including protection of the cardiovascular system, anti-cancer, anti-inflammatory, anti-neurodegenerative diseases, etc. The targets (proteins or genes) affected by Tan I against diseases involve Bcl-2, Bid, ITGA2, PPAT, AURKA, VEGF, PI3K, AKT, PRK, JNK, MMP ….
Tanshinone IIA: A Review of its Anticancer Effects - PubMed
网页2021年1月14日 · Tanshinone IIA (Tan IIA) is a pharmacologically lipophilic active constituent isolated from the roots and rhizomes of the Chinese medicinal herb Salvia miltiorrhiza Bunge (Danshen). Tan IIA is currently used in China and other neighboring countries to treat patients with cardiovascular system …
Tanshinones, Critical Pharmacological Components in Salvia …
网页Tanshinones are the main active ingredients in S. miltiorrhiza and exhibit significant pharmacological activities, such as antioxidant activity, anti-inflammatory activity, cardiovascular effects, and antitumor activity. Danshen dripping pill of Tianshili is an effective drug widely used in the clinical treatment of cardiovascular diseases.