Evolution of a minimal cell | Nature
网页2023年7月5日 · The minimal cell (JCVI-syn3B) has a synthetically constructed genome containing a subset of genes found in a corresponding non-minimal strain (JCVI-syn1.0). By reducing the chromosome from 901...
Treatment of rat cranial defect with autogenetic minimal …
网页After compound autogenetic minimal morselized bone graft and allogenic cells graft, rat cranial defect was repaired sooner, and the expression of osteocalcin and TGF-#beta#1 mRNA was much earlier.
Minimal Cells—Real and Imagined - PMC - National Center for ...
网页A minimal cell is one whose genome only encodes the minimal set of genes necessary for the cell to survive. Scientific reductionism postulates the best way to learn the first principles of cellular biology would be to use a minimal cell in which the functions of all genes and components are understood.
Treatment of rat cranial defect with autogenetic minimal …
网页2005年1月1日 · Europe PMC is an archive of life sciences journal literature.
The minimal genome comes of age | Nature Biotechnology
网页2016年6月9日 · A functional minimal genome would help broaden understanding of the requirements for life and demonstrate the ability to build synthetic organisms, and it might lead to...
Treatment of rat cranial defect with autogenetic minimal …
网页The combined therapy of minimal morselized bone and allogenic cells accelerate the repairment of cranial defect and the expression of cell factors.
Autogenesis: The evolution of replicative systems - ScienceDirect
网页1985年5月21日 · A theoretical model is introduced for the spontaneous emergence of replicative organization, called autogenesis. Autogenesis commences in a system by an organized “small” subsystem, referred to as AutoGenetic System Precursor (AGSP), which conveys replicative information to the system.
Synthetic Biology: Minimal cells, maximal knowledge | eLife
网页2019年3月12日 · An obvious way to start this endeavor is to study minimal cells, natural or synthetic organisms that contain only the bare minimum of genetic information needed to survive. By building and studying these very simplified cells – so simple they have been described as the ‘hydrogen atoms of biology’ ( Morowitz, 1984 ) – we may be able to ...
Comparative genomics, minimal gene-sets and the last …
网页2003年11月1日 · A minimal set of genes that is necessary and sufficient for sustaining a functional cell can be delineated either by computational comparisons of microbial genomes or experimentally by knocking...
Does Autogenic Semiosis Underpin Minimal Cognition?
网页2021年10月20日 · Since Deacon describes the autogen in cognitive terms, this article examines whether the autogen model can embody the critical disposition that underpins the emergence of minimal cognition. It finds that it does so, but argues that the autogenic system itself fails to be cognitive because it lacks the …