Neurohormone - Wikipedia
网页A neurohormone is any hormone produced and released by neuroendocrine cells (also called neurosecretory cells) into the blood. [1][2] By definition of being hormones, they are secreted into the circulation for systemic effect, but they can also have a role of neurotransmitter or other roles such as autocrine (self) or paracrine (local) messenger.
Neurohormone | Description, Types, Neurotransmission, & Function
网页A neurohormone is any of a group of substances that are produced by specialized neurosecretory cells of the nervous system and that are released into the blood, similar to hormones of the endocrine system.
Neurohormonal activation in heart failure with reduced ejection ...
网页Neurohormonal activation results in a series of coordinated responses that collectively work to restore cardiovascular homeostasis in the short-term. Sustained neurohormonal activation drives the progression of HFrEF through the deleterious effects exerted on the circulation and the myocardium
Neurohormonal Blockade in Heart Failure - PMC - National …
网页2016年9月26日 · A key feature of chronic heart failure (HF) is the sustained activation of endogenous neurohormonal systems in response to impaired cardiac pumping and/or filling properties. The clinical use of neurohormonal blockers has revolutionised the care of HF patients over the past three decades.
Hormones of the Cardiovascular System - Endotext - NCBI Bookshelf
网页2015年2月6日 · Neurohormonal systems play a critical role in cardiovascular homeostasis as well cardiovascular pathophysiology and diseases such as congestive heart failure, coronary artery disease, hypertension and chronic kidney disease. Neurohormonal activation is an important cause and therefore an important therapeutic target to treat cardiovascular ...
神經激素 - 维基百科，自由的百科全书
网页神經激素. 神经激素 （neurohormone）是由 神经内分泌细胞 （也称为神经分泌细胞）产生并释放到血液中的任何 激素。. [1][2] 它们被分泌到循环系统中发挥作用，但是它们也可以具有神经递质的作用或其他作用，例如自分泌（自身）或旁分泌（局部）的传递组织 ...
Neurohormone - an overview | ScienceDirect Topics
网页Neurohormonal Changes in Heart Failure. Neurohormones are formed by specialized neurosecretory cells, which because of their part in the nervous system structure, can act as a neurotransmitter as well as a hormone. In a pathologic state such as CRS, they play a role in mediating an oxidative stress or injury cascade that includes pervasive ...
Neurohormonal activation in heart failure with reduced ejection ...
网页2016年10月6日 · Neurohormonal activation is now known to be one of the most important mechanisms underlying the progression of heart failure, and therapeutic antagonism of neurohormonal systems has become the...
Neurohormonal Regulation of IKs in Heart Failure: Implications …
网页2020年8月31日 · The objective of this review is to summarize the current knowledge related to the regulation of the slow component of the delayed rectifier potassium current in response to HF‐associated stimuli, including the intracellular pathways involved and the specific regulatory mechanisms.
Mechanisms and Models in Heart Failure | Circulation Research
网页2021年5月13日 · The neurohormonal model led to the use of beta-adrenergic blocking agents to block the deleterious effects of the sympathetic nervous system in the heart, and angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and aldosterone antagonists to block the deleterious effects of RAAS.