Perineural invasion - Wikipedia
网页In pathology, perineural invasion, abbreviated PNI, refers to the invasion of cancer to the space surrounding a nerve. It is common in head and neck cancer, prostate cancer and colorectal cancer.
Perineural Invasion in Prostate Cancer: What It Means for You - Healthline
网页2022年10月24日 · Perineural invasion (PNI) means that cancer cells are growing inside or alongside a nerve. A nerve is a bundle of fibers made up of cells called neurons. Nerves send and receive signals from your...
Perineural Definition & Meaning | Merriam-Webster Medical
网页The meaning of PERINEURAL is occurring about or surrounding nervous tissue or a nerve.
Perineural involvement: what does it mean? - PubMed
网页Perineural invasion is an important mechanism for local spread in certain malignant cutaneous neoplasms and is associated with aggressive tumor growth, increased frequency of recurrence, and increased morbidity and mortality. Thus, perineural invasion is often used both as a marker of malignancy and an indicator of aggressive behavior.
Mechanisms of Perineural Invasion - PMC - National Center for ...
网页2016年3月10日 · Perineural invasion (PNI) is the neoplastic invasion of nerves. PNI is widely recognized as an important adverse pathological feature of many malignancies, including pancreatic, prostate, and head and neck cancers and is …
Pathology of Perineural Spread - PMC - National Center for ...
网页2016年2月26日 · Perineural tumor growth is one of the important mechanisms by which cancers extend beyond their primary site of development. Infrequently, it may be the only mechanism of metastatic spread. Two interrelated types of perineural tumor growth exist: perineural invasion (PNI) and perineural spread (PNS).
The roles of perineuronal nets and the perinodal extracellular matrix ...
网页2019年7月1日 · Perineuronal nets (PNNs) are extracellular matrix (ECM) chondroitin sulfate proteoglycan (CSPG)-containing structures that surround the soma and dendrites of various mammalian neuronal cell...
Perineural invasion in cancer: a review of the literature
网页2009年8月1日 · Perineural invasion (PNI) is the process of neoplastic invasion of nerves and is an under-recognized route of metastatic spread. It is emerging as an important pathologic feature of many malignancies, including those of the pancreas, colon and rectum, prostate, head and neck, biliary tract, and stom ….
Perineural spread in head-and-neck malignancies: Imaging …
网页2021年6月29日 · Perineural spread (PNS) represents the tumor’s ability to disseminate along nerves. The aim of this article is to review the relevant literature about the PNS in head-and-neck tumors. The important information for imaging analysis is summarized in a diagnostic flowchart.
Role of the nervous system in cancers: a review
网页2021年4月12日 · 1. Nerves, as components of the tumor microenvironment, are associated with cancer outcomes. 2. Nerve transmitters and neurotrophic factors play an essential role in tumor progression. 3....