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网页2 Minute Medicine Rewind September 16, 2024. by Jayden Berdugo and 1 others. September 16, 2024. Sleep patterns, physical activity, genetic susceptibility, and incident rheumatoid arthritis: a prospective cohort study 1. In this prospective cohort study, a healthy sleep pattern and moderate levels of physical activity...
Datopotamab deruxtecan may be a novel improvement for …
网页19 小时之前 · 1. Compared to chemotherapy, patients with inoperable hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) breast cancer receiving the antibody-drug conjugate (ADC) datopotamab deruxtecan (Dato-DXd) experienced significant improvements in progression-free survival (PFS) with a …
Ponsegromab for the Treatment of Cancer Cachexia
网页18 小时之前 · Ponsegromab for the Treatment of Cancer Cachexia. 1. Ponsegromab at increasing doses resulted in a mean increase in body weight compared to placebo; 1.22 kg (2.21%) in the 100-mg group, 1.92 kg (2.99%) in the 200-mg group, and 2.81 kg (5.46) in the 400-mg group. 2. Adverse events of any cause were reported in 67%-74% in the …
2 Minute Medicine Rewind September 23, 2024
网页1 天前 · September 23, 2024. in Weekly Rewinds. Reading Time: 9 mins read. Preconception and Early-Pregnancy Body Mass Index in Women and Men, Time to Pregnancy, and Risk of Miscarriage. 1. Preconception BMI outside of the normal category in women and men was associated with lower fecundability and subfertility. 2.
#VisualAbstract: No Difference in Risk Seen in Long-Term Oxygen …
网页20 小时之前 · 2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting.
GSK: Depemokimab Monoclonal Antibody Reduces Asthma Attacks
网页2024年9月16日 · Depemokimab is a monoclonal antibody that blocks human interleukin-5 (IL-5) binding to its receptor. IL-5 is a known core cytokine in type 2 inflammation that drives the underlying pathology in immune-mediated conditions. IL-5 is responsible for the growth, activity, and survival of eosinophils. In more than 80% of patients with severe asthma ...
Landmark Trials & Summaries: The Classics in Medicine - 2 Minute …
网页A deep understanding of these trials is paramount for every physician, healthcare professional, and trainee, as it lays the foundation for evidence-based clinical decisions made daily. 2MM+ Subscriber Exclusive Access: The Online Edition of The Classics Series™ includes The Classics in Medicine™ textbook and all deep-dive sub-specialty ...
Phase I trial of novel CAR-T cell therapy for pediatric midline gliomas
网页2024年8月10日 · This phase I trial sought to examine whether C7R could safely enhance the antitumour activity of CART directed against the disialoganglioside, GD2, in children. 11 patients aged 12 months to 21 years (median age = 12.0 years, 45.5% female) with GD2-positive DMG or other progressive GD2-expressing CNS tumours were selected and …
Teplizumab effective in maintaining β-cell function in type 1 diabetes
网页2024年1月5日 · 1. In this randomized-controlled trial, two 12-day courses of teplizumab improved C-peptide levels compared to placebo at week 78 in patients with stage three type 1 diabetes. 2. No significant differences were observed between the teplizumab and placebo groups with respect to secondary clinical outcomes, including clinically relevant …
The ARMA trial: Lower tidal volume ventilation in ALI/ARDS …
网页1. The trial was terminated early when the data demonstrated that lower tidal volume ventilator settings in ALI/ARDS patients led to a significant decrease in in-hospital mortality. 2. Low tidal volume ventilation also led to an increase in ventilator-free days and a decrease in the number of days with systemic organ failure. There was no.