Thermostability - Wikipedia
网页In materials science and molecular biology, thermostability is the ability of a substance to resist irreversible change in its chemical or physical structure, often by resisting decomposition or polymerization, at a high relative temperature.
Thermostability - an overview | ScienceDirect Topics
网页Thermostability is the most desired trait of any industrial enzyme which allows fast rate of reaction at elevated temperature thereby decreasing the usage of enzyme. Although the commercial lignocellulosic ethanol production began in different parts of the world, still continuous research is desirable to improve thermostability of the cellulase ...
Thermal stability enhancement: Fundamental concepts of protein ...
网页2022年8月1日 · Two protein states are involved in the heat-induced denaturation: the natively folded state (N) and the unfolded (denatured) state (U). This process can be described variously as “thermostability”, “thermal stability” and “thermodynamic stability”. In the literature, these stability concepts are often used interchangeably.
Insights on protein thermal stability: a graph representation of ...
网页2018年12月10日 · Results. Here, we present a novel graph-theoretical framework to assess thermal stability based on the structure without any a priori information. In this approach we describe proteins as energy-weighted graphs and compare them using ensembles of interaction networks.
Analysis of Protein Thermostability Enhancing Factors in …
网页2013年8月18日 · Protein thermostability is, therefore, the preservation of the unique structure and chemical properties of polypeptide chains under extreme temperatures. 1 Thermostability is a very important property of enzymes because it enhances productivity in industry, as enzymes operate at higher temperatures where more reagents and compounds are ...
Tuning Enzyme Thermostability via Computationally Guided …
网页2022年5月25日 · We recently introduced a novel method for enzyme thermostabilization that relies on the computationally guided installation of genetically encoded thioether “staples” into a protein via cysteine alkylation with the noncanonical amino acid O -2-bromoethyl tyrosine (O2beY).
ProtDataTherm: A database for thermostability analysis and
网页2018年1月29日 · Protein thermostability engineering is a powerful tool to improve resistance of proteins against high temperatures and thereafter broaden their applications. For efficient protein thermostability engineering, different thermostability-classified data sources including sequences and 3D structures are needed for different protein families.
ProtDataTherm: A database for thermostability analysis and …
网页2018年1月29日 · Protein thermostability engineering is a powerful tool to improve resistance of proteins against high temperatures and thereafter broaden their applications. For efficient protein thermostability engineering, different thermostability-classified data sources including sequences and 3D structures are needed for different protein families.
Thermostability - an overview | ScienceDirect Topics
网页“Thermostability” is defined by capacity of an enzyme to retain its active structural conformation at a selected high temperature for a prolonged period. Thermostable enzymes, have found a number of commercial applications (Demirjian et al., 2001).
Engineering protein thermostability using a generic activity ...
网页2013年12月19日 · By combining the method with a random mutagenesis procedure, we successfully identify thermostable variants from 10 diverse and challenging proteins, including several biotechnologically important...