Urokinase Uses, Side Effects & Warnings - Drugs.com
网页Urokinase is a thrombolytic (THROM-bo-LIT-ik) drug, sometimes called a "clot-busting" drug. It helps your body produce a substance that dissolves unwanted blood clots. Urokinase is used to treat blood clots in the lungs.
Urokinase - Wikipedia
网页Urokinase, also known as urokinase-type plasminogen activator (uPA), is a serine protease present in humans and other animals. The human urokinase protein was discovered, but not named, by McFarlane and Pilling in 1947. [5]
Urokinase: Uses, Interactions, Mechanism of Action - DrugBank …
网页2005年6月13日 · Urokinase is a low molecular weight form of human urokinase used to treat pulmonary embolism and myocardial infarction as well as to clear IV lines.
尿激酶 - 百度百科
网页尿激酶，是从健康人尿中分离的，或从人肾组织培养中获得的一种酶蛋白，由分子量分别为33000 （LMW-tcu-PA）和54000（HMW-tcu-PA）两部分组成，主要用作溶栓药，直接作用于内源性纤维蛋白溶解系统，能催化裂解纤溶酶原成纤溶酶，后者不仅能降解纤维蛋白凝 …
尿激酶 - 维基百科，自由的百科全书
网页尿激酶（英語： Urokinase ）由肾脏生成，可直接激活纤维蛋白溶酶原转变成纤溶酶。尿激酶是从尿中提取的第一代天然溶栓药。 [6]
Urokinase injection - Cleveland Clinic
网页UROKINASE (yoor uh KAHY neys) breaks up blood clots. It is used to treat large blood clots formed in the lungs. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
Outcomes and Treatment Complications of Intravenous Urokinase ...
网页2021年7月12日 · Like alteplase, urokinase is a plasminogen activator. Urokinase has been approved by the China Food and Drug Administration and recommended in the latest Chinese stroke guidelines to use for intravenous thrombolysis in …
Soluble Urokinase Receptor and Acute Kidney Injury
网页2020年1月29日 · In experimental studies, we used a monoclonal antibody to urokinase plasminogen activator receptor (uPAR) as a therapeutic strategy to attenuate acute kidney injury in transgenic mice receiving...
Production and purification of urokinase: A comprehensive review
网页2006年1月1日 · Based on these observations, urokinase, derived primarily from urine, is a very popular cardiovascular agent. However, due to extremely low concentrations of urokinase in human urine, human cells cultured in vitro provide a superior alternative for the production and purification of urokinase [2].
Urokinase and its Receptors in Chronic Kidney Disease
网页This review will summarize current knowledge about the serine protease urokinase-type plasminogen activator and its high affinity receptor uPAR/CD87 as it pertains to chronic kidney disease (CKD) progression. An emerging theme is that the effects of PAI-1 and uPAR appear to be organ- and site-specific.