A research team identified Ru5 as a potent antitumor agent by screening a panel of ruthenium(II) polypyridine complexes ...

GlobalData’s report assesses the drugs in the Copper Transporting ATPase 2 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.

Secondary efficacy analyses of the pivotal SEQUOIA-HCM trial continued to favor aficamten, supporting a potential role for ...

Phase 1 study showed significant lung uptake and enhanced epithelial lining fluid (ELF) and alveolar macrophage (AM) ...

The prize was for the determination of the detailed mechanism by which ATP shuttles energy. The enzyme which makes ATP is called ATP synthase, or ATPase, and sits on the mitochondria in animal cells ...

Nonetheless, all remodelers contain a subunit with a conserved ATPase domain. In addition to the conserved ATPase, each remodeler complex also possesses unique proteins that specialize it for its ...

a preclinical Polθ ATPase inhibitor program; as well as additional, undisclosed preclinical programs. For more information, please visit reparerx.com and follow @Reparerx on X (formerly Twitter ...

NaCl-induced alterations in cytotoxic T lymphocytes are associated with sodium-induced increased Na+/K+-adenosine triphosphatase (ATPase) activities and membrane hyperpolarization, which amplifies ...

University of Galway will lead a new research project aimed at understanding the development of neurodegenerative diseases.

Istaroxime significantly improved primary endpoint of the systolic blood pressure profile over six hours and showed significant improvements in ...

谈及癌症转移，一句话总结就是一个巴掌拍不响。这是纪念斯隆-凯特琳癌症中心（MSK）研究人员领导的一项新研究的主要发现之一：TGF-β和RAS信号通路共同促进了肺腺癌的扩散，而肺腺癌是全球癌症死亡的主要原因。近日，一篇发表在国际杂志 Cell 上题为 “TGF-β and RAS jointly unmask primed enhancers to drive metastasis” ...