该研究发现了一种直接且特异性的gasdermin D（GSDMD）小分子激动剂——DMB，其能够在无需切割GSDMD的情况下激活GSDMD介 ... 在肿瘤中表达外源性GSDME可以增强肿瘤肿瘤浸润杀伤性细胞的功能，这可能是由于细胞毒性T淋巴细胞（CTL）递送的GzmB将GSDME切割并激活，从而 ...

DMB is embarking on a limited six-show fall tour, starting in Pittsburgh and concluding with two nights at New York City’s ...

在抗癌的研究领域，科学家们一直在寻找既能有效杀死肿瘤细胞，又不会对正常组织造成严重副作用的治疗方法。 近年来，焦亡（pyroptosis） 这种新发现的细胞死亡机制，逐渐成为癌症研究中的重要课题。

With over 100 acts spread across five stages at Bourbon & Beyond, you probably missed a thing or two. Here are five of our ...

On Sept. 28-29, the annual music celebration is bringing some of the biggest names in music like Noah Kahan, Foo Fighters, ...

You may have been surprised to see the Dave Matthews Band among the upcoming inductees this year into the Rock and Roll Hall ...

As Noah Kahan's new album Live from Fenway Park debuts on the Billboard 200, the rising superstar matches both Dave Matthews ...

David Bach is the CEO of Unity House a Capital Region human services organization providing crisis intervention, advocacy, ...

Festival time - when Louisville becomes the center of the music universe for two straight weeks as we host two of the largest ...

The real magic of Bourbon & Beyond lies in dipping a toe into multiple offerings throughout each day. Here's what we ...

It's called "the world's largest bourbon and music festival" for good reason. Here is your day-by-day music and food guide to ...

There will culinary demonstrations featuring chefs from such nationally known programs as “The Mind of a Chef” and “Chopped.” ...