Unlike other central nervous system (CNS) stimulants, modafinil and its R-enantiomer (armodafinil) do not cause an immediate surge in neurotransmitters such as dopamine, norepinephrine, and histamine.
It is usually the case that a very closely related analog (for example, enantiomer, diastereomer, regioisomer, ± methyl) is inactive in the biochemical assay—this is an excellent negative ...
Each of the mirror images of a molecule that is not superimposable is called an enantiomer. "In nature and in pharmacology there are multiple examples in which the two enantiomers have different ...
Pregabalin is the pharmacologically active S-enantiomer of racemic 3-isobutyl γ-aminobutyric acid. Pregabalin has demonstrated efficacy in the management of neuropathic pain associated with ...
The mechanism of antidepressant action of escitalopram, the S-enantiomer of racemic citalopram, is presumed to be linked to potentiation of serotonergic activity in the CNS resulting from its ...
Velusetrag Activation of peristalsis and acceleration of intestinal transit. Elobixibat Enantiomer of 1,5-benzothiazepine. Bond and inhibits the ileal bile acid transporter. Abdominal pain ...