In a study of centenarians conducted in collaboration with scientists at Albert Einstein College of Medicine, the variant, affecting a mitochondrial microprotein called humanin, was found to be more ...

The microprotein in the mitochondria (green) and in the nucleus (blue) was overexpressed in human cells. The yellow and pink areas show that the signal of the microprotein overlaps with the ...

The variant, located in a mitochondrial microprotein dubbed SHLP2, was found to be highly protective against Parkinson's disease; individuals with this mutation are half as likely to develop the ...