The mitotic checkpoint is seldom lost or weakened in human tumours. Mitotic checkpoint overactivation is a more frequent observation in human tumours and is sufficient to generate CIN in vivo and ...
Homologous recombination maintains genomic stability in mammalian mitotic cells through precise templated repair of DNA double-strand breaks and other lesions. The outcome of homologous ...
Their results provide a novel insight into mitotic chromosome condensation in living human cells. Their work is published in the journal Proceedings of the National Academy of Sciences on August ...
(A) Histone staining images and OI-DIC density imaging of human living cells in the interphase (the phase between cell divisions, left) and mitotic phase (right). The bottom two rows are OI-DIC ...