Pulmonary function remained stable -- and in some ways improved -- among patients with sickle cell disease (SCD) who ...

The goal of HCT is to cure an underlying malignancy or hematologic disorder. The procedure can be performed in an inpatient ...

For the research, Ruhl and her team studied 97 patients with sickle cell disease who underwent a low-intensity, or non-myeloablative, blood stem cell transplant between 2004–2019 at the NIH's ...

Discover new insights into the effects of haematopoietic cell transplant on pulmonary function in adults with sickle cell ...

One of Dr. Storb’s major scientific contributions is the non-myeloablative transplant. Non-myeloablative transplant, sometimes called "mini-transplant," involves minimal pre-transplant radiation. It ...

A few days before Casgevy is infused, patients undergo myeloablative chemo to wipe out their bone marrow, removing unhealthy blood stem cells and making room for the new, edited versions.

Reduced-intensity conditioning regimes for HSCT candidates have similar short-term outcomes as HSCT candidates receiving myeloablative conditioning. Partial HLA-matched cord blood is a viable stem ...

To reduce duration of neutropenia and related sequelae in patients with nonmyeloid malignancies undergoing myeloablative chemotherapy followed by bone-marrow transplantation (BMT). To mobilize ...

Behçet's disease (BD) is a systemic large-vessel vasculitis characterized by a wide clinical spectrum including recurrent oral and genital ulcerations, uveitis, and vascular, neurological ...

Zevalin-mini allo; The major goal of this project is to conduct a Phase II trial evaluating the efficacy of Non-myeloablative 90Y-anti-CD20 Antibody, Fludarabine, Low-Dose total body irradiation (TBI) ...