编辑丨王多鱼排版丨水成文普遍的观点认为压力对健康有负面影响,并加速生物衰老。然而,压力如何影响衰老过程和预期寿命在很大程度上仍然是未知的。2024年11月11日,明尼苏达大学的研究团队在 Nature Aging 期刊发表了题为:Chronic ...
【导读】前列腺癌是全球男性中第二常见的癌症。最近的研究强调了il6st介导的信号通路在各种癌症的发生和发展中发挥的关键作用,特别是通过过度激活的STAT3信号通路。然而,IL6ST/STAT3在前列腺癌中介导的分子程序尚不清楚。10月31日,奥地利维 ...
The RaDAR (RanGDP/AR) pathway is acquired by the most common familial melanoma associated CDKN2A mutation, leading to nuclear accumulation of mutant p16ink4a. It is frequently used by AR ...
Zizyphi spinosi semen demonstrates neuroprotective effects, improving cognitive function and reducing amyloid and tau pathology in models of aging and dementia.
The study aimed to evaluate its impact on QOL and its association with the aging biomarker, p16INK4a. "…this pilot study ...
Shi J, Xu J, Chen Y, Li J, Shen L, Li JJ, Li W. The concurrence of DNA methylation and demethylation is associated with transcription regulation. Nature Communications. 2021 Sept 6; 12(1):5285. PMID: ...