The RaDAR (RanGDP/AR) pathway is acquired by the most common familial melanoma associated CDKN2A mutation, leading to nuclear accumulation of mutant p16ink4a. It is frequently used by AR ...
Zizyphi spinosi semen demonstrates neuroprotective effects, improving cognitive function and reducing amyloid and tau pathology in models of aging and dementia.
Shi J, Xu J, Chen Y, Li J, Shen L, Li JJ, Li W. The concurrence of DNA methylation and demethylation is associated with transcription regulation. Nature Communications. 2021 Sept 6; 12(1):5285. PMID: ...