Dr. Katharine Marder, a psychiatrist with UC Davis Health, works in the clinic for treatment-resistant depression. That is depression that hasn't gotten better with traditional treatments. It affects ...
In treatment-resistant bipolar depression ... symptoms and functioning in people with bipolar depression, particularly those experiencing severe hypersomnia (excessive sleepiness).
For treatment-resistant depression ... People with long-term or severe depression may lose some important connections in their brains (called synapses) that let nerve cells communicate.