Thus, tumor cytolysis by PMN appears to be dependent on both oxidative and non-oxidative mechanisms, whereas inhibition of NK cytotoxicity requires the generation of ROI.
The constant region triggers effector functions (phagocytosis, cytolysis, or initiation of complement cascade followed by cell lysis) by linking the complex to other cells of the immune system.
In the Huse lab, we combine imaging technology with synthetic chemistry and materials science to understand how immune cells communicate. Winer, B. Y., Settle, A. H ...
TNF-α is a potent inducer of the inflammatory response, a key regulator of innate immunity and plays an important role in the regulation of Th1 immune responses against intracellular bacteria and ...
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