It uses a ligand-dependent destabilization domain that is fused to a protein of interest. Addition of a membrane-permeant small molecule, Shield1, reversibly stabilizes the fusion protein in a ...

Novel method identified protein degraders that target Pin1, a protein involved in pancreatic cancer development.

In drug discovery, targeted protein degradation is a method that selectively eliminates disease-causing proteins. A ...

Despite the setbacks Russia faces in its ongoing invasion of Ukraine, Wagner Group mercenaries, which have rebranded as “Africa Corps” in certain areas, remain firmly entrenched across Africa.

German Foreign Minister Annalena Baerbock visited Beirut on Wednesday, warning that the conflict between Israel and Hezbollah ...

"The destabilization ... that Venezuela has imposed on other Latin American countries is huge," she said. "I've just heard 7.8 million people have left Venezuela. Most of them are coming into other ...

China’s efforts to contain India may be less important than smaller countries’ desire to counterbalance Indian influence.

A team of scientists has used a novel approach to identify protein degraders that target Pin1, a protein involved in pancreatic cancer development.

The Ugandan government has decided to significantly reduce its external borrowing by 98 percent in an effort to control the ...

German Foreign Minister Annalena Baerbock on Wednesday warned the conflict between Israel and Hezbollah could lead to the "complete destabilization" of Lebanon, with dangerous consequences for the ...

President Biden lauds Moldovan incumbent Maia Sandu's reelection, saying "Russia sought to undermine" the country's ...

The Arewa Youth Consultative Forum (AYCF) has condemned in strong terms “the recent protests and disturbances orchestrated ...