在这项最新研究中，研究团队发现了GSDMD的一种小分子激动剂——DMB（6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline），它能激活非切割依赖的GSDMD的孔道形成。DMB曾作为一种口服小分子GLP-1受体激动剂，但由于效果不及相应的生物制剂，没有进一步进行临床开发。

A study published in the Environmental Science and Technology journal reveals that many cars have carcinogenic flame ...

Protect your children against disease-carrying insects!” screamed the advertising poster for the ‘killer’ wallpaper.

They are also stacking additional tolerance traits that can be paired with other herbicides, such as dicamba (3,6-dichloro-2-methoxybenzoic acid), glufosinate (phosphinothricin) and 2,4-D ...

Many store-bought cleaning products out there are basically poison. They contain a slew of toxic chemicals that may quickly ...

In 10 UP districts, a new chemical spray will protect homes from mosquitoes, replacing DDT, covering 1,000 villages to combat ...

But samples from the bottom of the harbor have tested positive for trace amounts of harmful chemicals including mercury, polychlorinated biphenyls (PCBs) and the pesticide dichloro-diphenyl ...

HSE will provide separate updates on the renewal decisions and future expiry date postponements captured within this overall decision when relevant. 2) Under the GB BPR, active substance approvals ...

The study assessed the levels of organophosphates that children between the ages of 3 and 11 were exposed to, and homed in on one called "bis (1,3-dichloro-2-propy) phosphate." They found that ...

These chemicals, including tris (1,3-dichloro-2-propyl) phosphate (TDCIPP) and tris (2-chloroethyl) phosphate (TCEP). Why is this a problem? These chemicals are linked to cancer, neurological ...