When you have complement 3 (C3) glomerulopathy, a problem with your immune system can damage your kidneys. You’ll take medicine to control your immune system and protect your kidneys.

Obesity, uncontrolled diabetes and hypertension are the main risk factors for the development of kidney diseases. In this ...

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A recent study has shown that the prevalence of glomerular damage in adults with various forms of sickle cell anemia is much higher than previously thought. Guasch and colleagues investigated the ...

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Also known as membranous glomerulopathy – MN is one of the many glomerular diseases causing nephrotic syndrome, characterized by massive proteinuria and clinically presents with peripheral edema ...

The systemic form of pegcetacoplan is also being developed for C3 glomerulopathy (C3G) and immune complex glomerulonephritis (IC-MPGN), with results due later this year. The success of clinical ...

Meanwhile, ADX-097 provides localized inhibition of the complement system to manage immune-mediated kidney diseases, including lupus nephritis, IgA nephropathy, C3 glomerulopathy, and ANCA ...

Zaltenibart is under clinical development by Omeros and currently in Phase II for Paroxysmal Nocturnal Hemoglobinuria.

include paroxysmal nocturnal haemoglobinuria (PNH), atypical haemolytic uraemic syndrome (aHUS), C3 glomerulopathy (C3G), and idiopathic membranous nephropathy (IMN).

CFI deficiency can also manifest in renal conditions such as atypical hemolytic uremic syndrome, complement 3 glomerulopathy, or immune-complex membranoproliferative glomerulonephritis.