A major focus of our work is on POGLUT1 and other glycosyltransferases responsible for the addition of O-linked glycans to epidermal growth factor-like (EGF) repeats. Specifically, we would like to ...
Unlike other biomolecules, glycans are not directly encoded by DNA in the genome. Instead, they are built from simple building blocks by molecular machines called glycosyltransferases. When ...