The UAB Gnotobiotic Mouse Core facility (GMC), provides gnotobiotic animal services to UAB investigators. These services include access to existing gnotobiotic mouse models, assistance in developing ...
This removes significant cost and logistical barriers to studying the microbiota in these models. Gnotobiotic animals require specialized housing in order to ensure their sterility or prevent ...
The Gastrointestinal Experimental Model Systems Core (GEMS) is subdivided into two subcores: organoid and gnotobiotic sub-cores. The core’s centralized services support exciting scientific ...
The resulting fecal library can be used for multiple analyses, as well as transplantation into gnotobiotic mice for the development of animal models. We have procedures in place for the collection, ...
They orally inoculated gnotobiotic (germ-free) mice with equal numbers of isogenic, wild-type B. fragilis (GA3 T6SS only) and the GA3/GA1 ICE transconjugant. The transconjugant quickly outcompeted ...
Dietary protein absorption in neonatal mammals and fishes relies on the function of a specialized and conserved population of highly absorptive lysosome rich enterocytes (LREs). The gut microbiome has ...
Infection with HumanImmuno-deficiency Virus-I (HIV-1) results in a profound and selective loss of CD4+ T cells, leading toprogressive immunodeficiency that culminates in Acquired Immunodeficiency ...
This important study leverages an impressive and comprehensive longitudinal 16S microbiome dataset from baboons to provide insights regarding the use of a microbiome-based clock to predict biological ...