2004; Robertson, 2002; Jones & Baylin, 2002). Hypermethylation of CpG islands can cause tumors by shutting off tumor-suppressor genes. In fact, these types of changes may be more common in human ...

The appearance and behaviour of cells are determined by the genes expressed in that cell. The abnormal behaviour of cancer cells can thus be explained by invoking quantitative and/or qualitative ...

Researchers sought to determine whether DNA methylation markers could be helpful in risk stratification for patients with AML and normal cytogenetics.

For instance, abnormal CpG island hypermethylation is frequently observed in cancers and is often linked to tumor suppressor ...

For instance, abnormal CpG island hypermethylation is frequently observed in cancers and is often linked to tumor suppressor genes. The review also points out the potential of epigenetic drugs in ...

More information: Abhimanyu et al, TCA metabolism regulates DNA hypermethylation in LPS and Mycobacterium tuberculosis ...

Aim: Health plan coverage policies can influence utilization of genetic tests. Our goal was to characterize the current state of test-related policies from US private payers. Methods: We searched ...

Our analysis of DNA methylation offers additional evidence supporting the involvement of altered gene expression of KP enzymes in depression, since hypermethylation is frequently associated with gene ...

DURECT Corporation (Nasdaq: DRRX), a late-stage biopharmaceutical company pioneering the development of epigenetic therapies ...

Shi J, Xu J, Chen Y, Li J, Shen L, Li JJ, Li W. The concurrence of DNA methylation and demethylation is associated with transcription regulation. Nature Communications. 2021 Sept 6; 12(1):5285. PMID: ...