Plucking hair accelerates their growth cycle and shortens the lifespan of these melanocyte stem cells. This has led Aoki to ...

Research Interests: Somatic Stem Cells and Aging, Genetic Mechanisms of Stem Cell Maintenance, Therapeutic Approaches to Tissue Rejuvenation, Mouse Models of Hair Graying, Melanocyte Stem Cells and ...

Skin pigmentation disorders affect people across the world. One of them, vitiligo, is said to have a worldwide incidence of 1 ...

Another element in the leptin signaling pathway is α-melanocyte-stimulating hormone (α-MSH), which is actually a fragment of the precursor protein POMC. Mutations in the POMC gene cause a rare ...

She continued her research work as a postdoc in Ze´ev Ronai´s laboratory at SBP Discovery in La Jolla, USA where she analyzed the role ATF2 in UV-induced melanocyte migration and melanomagenesis.

They discovered that ALX3, a transcription factor, binds to the promoter and represses MITF, a known regulator of melanocyte differentiation. To see if this newly discovered mechanism controlling ...

As hair ages, sheds and then repeatedly grows back, increasing numbers of the melanocyte stem cells become sluggish at their job. The stem cells stop roaming around the follicle and become fixed ...

It can take up to 1 year to see a significant response with topical immunosuppressants and narrowband ultraviolet B treatment ...

“Heat styling tools and chemical treatments can damage follicles, which can potentially accelerate greying,” says Birch.

In particular, by suppressing MMP2, the hope is that pigment-producing cells will return to the skin.” Reference: Yang F, ...

Dark spots, brown patches, redness. Skin discoloration can appear in myriad ways, and often sticks around. But the best serum ...

Our lab uses human iPS and ES cells for modeling human disorders of the brain and peripheral nervous system such as Parkinson’s disease, familial dysautonomia, Herpes Simplex encephalitis and ...