Research Interests: Somatic Stem Cells and Aging, Genetic Mechanisms of Stem Cell Maintenance, Therapeutic Approaches to Tissue Rejuvenation, Mouse Models of Hair Graying, Melanocyte Stem Cells and ...
The localized gene correction was maintained for at least three months, suggesting that melanocyte precursors may have been converted. The same group previously published an in vitro study showing ...
She continued her research work as a postdoc in Ze´ev Ronai´s laboratory at SBP Discovery in La Jolla, USA where she analyzed the role ATF2 in UV-induced melanocyte migration and melanomagenesis.
They discovered that ALX3, a transcription factor, binds to the promoter and represses MITF, a known regulator of melanocyte differentiation. To see if this newly discovered mechanism controlling ...
As hair ages, sheds and then repeatedly grows back, increasing numbers of the melanocyte stem cells become sluggish at their job. The stem cells stop roaming around the follicle and become fixed ...
Our lab uses human iPS and ES cells for modeling human disorders of the brain and peripheral nervous system such as Parkinson’s disease, familial dysautonomia, Herpes Simplex encephalitis and ...