Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use. Diabetes 49 , 999–1005 (2000). Article CAS PubMed Google Scholar ...

They had no reason, however, to suspect that it had mitogenic activity. Because VPF was not purified to homogeneity and sequenced, the identity of this protein remained unknown at that time.

Treatment directed at reducing the mitogenic effects of estrogen through blockade of the ERs was the first (Beatson 1896), and remains the most frequently prescribed form of breast cancer therapy. But ...

are a family of secreted polypeptides that show angiogenic and mitogenic activities. The significance of VEGFs and receptors in tumorigenesis, angiogenesis, and neuroprotection makes them ...

One possibility is that in an attempt to overcome the inhibition within the metabolic insulin-signaling pathway, hyperinsulinemia may continue to stimulate the mitogenic insulin-signaling pathway ...

Glucocorticoids mitigate the mitogenic effect of excess estrogen in endometrial tissue; therefore, reduced glucocorticoid activity through HSD11B1 may facilitate estrogen-induced endometrial cell ...

In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...