For patients with refractory GERD who do not have esophagitis, possible etiologies include nocturnal gastric acid breakthrough, nonacid GER, missed GER or other diseases such as achalasia ...

GER is the second most common cause of chronic cough when GER-related cough is defined as a cough that is improved or resolved by GER therapy; nonacid or weakly acidic GER can elicit cough Up to ...

Nonacid reflux events were somewhat, but not significantly, more common with PPI therapy than with placebo. Sleep-related acid reflux events were more common with placebo than with PPI therapy (P ...