机器学习相比于传统统计方法所依赖的严格假设，能够捕捉非线性关系、蛋白质间的相互作用关系等生物学特性。其已开始在疾病早期诊断和标志物识别等领域发挥作用，特别是在处理高维度复杂数据时表现出色。

利用帕金森病全基因组基因分型项目的GWAS数据，研究团队进行了多组织联合分析，识别了48个基因，并且评估了这些基因在帕金森病大脑中各脑细胞类型的差异表达。帕金森病关联上调基因包括MAPT、TMEM163和KAT8，主要富集于少突胶质细胞，而大多数下调 ...

A small panel of circulating biomarkers may reliably distinguish hypertrophic cardiomyopathy (HCM) from similar conditions that cause left ventricular hypertrophy (LVH), researchers found. From ...

详情请点击右方：发表SCI论文首选NHANES医学数据库，现在2021-2023新一轮数据发布了，太给力! 2024年10月15日，浙江大学医学院附属第二医院学者团队在顶级期刊Nature子刊《Nature Communications》（医学一区top，IF=14.7）上发表了题为“Plasma proteomic and polygenic profiling improve risk str ...

At ASHG, Seer showcased its Proteograph product suite which it claims delivers proteomic insights that complement and ...

This review provides a comprehensive overview of the latest candidate proteomic biomarkers of venous thrombosis and of the proteomics studies relevant to its pathophysiology, some of which seem to ...

Discover more with the first and only technology that can measure 7,000 proteins over a broad range of concentrations. Built on 20 years of pioneering proteomics technology, The SomaScan Assay enables ...

This important manuscript provides insights into the competition between Splicing Factor 1 (SF1) and Quaking (QKI) for binding at the ACUAA branch point sequence in a model intron, regulating exon ...

Seer’s foundational technologies redefine how the research community approaches proteomic analysis, making it possible to tackle complex biological questions with an unprecedented level of depth, ...

A prospective study with 15,000 subjects for lung cancer, initiated in 2023, is underway to support the IVD product ...