First, sepiapterin is a precursor compound that is rapidly absorbed and converted intracellularly to tetrahydrobiopterin (BH4), a critical cofactor of PAH. Sepiapterin also has an independent ...

Rabies is associated with tetrahydrobiopterin deficiency and altered neurotransmission. Rabies patients develop generalized intracranial vasospasm. Ribavirin inhibits timely development of rabies ...

A GTP-cyclohydrolase-deficient mouse model of DYT5 shows metabolic parameters that are similar to those in humans with this disorder — low levels of tetrahydrobiopterin, catecholamines ...

Professor Carsten Carlberg has published a comprehensive new textbook, "Gene Regulation and Epigenetics: How Science Works," which presents the current understanding of gene regulation and ...

First, sepiapterin is a precursor compound that is rapidly absorbed and converted intracellularly to tetrahydrobiopterin (BH4), a critical cofactor of PAH. Sepiapterin also has an independent ...