Figure 1: A schematic diagram illustrating decidual NK cells as switchboards, licensed and educated to control trophoblast invasion and vascular remodeling and to interact with dendritic cells ...
The blastocyst has only three parts: the inner cell mass (A), the trophoblast cell layer (B), and the inner cell cavity (C). The inner cell mass is the part that in nature goes on to form the ...
I can see the trophoblast, which would normally become the placenta, enveloping the embryo. And it includes the cavities - called lacuna - that fill with the mother's blood to transfer nutrients ...
They named the monkey "ReTro", after the scientific method, called "trophoblast replacement", used to produce the animal. The RSPCA said it had grave misgivings about the research. "There is no ...
These pluripotent cells are the most ubiquitous of all. Once removed from the blastocyst they lack the outer trophoblast structures for continued embryonic development, but they can theoretically ...
Jorge Lopez-Tello, a researcher in the University of Cambridge's Center for Trophoblast Research, first author of the report. He added, "This means future treatments for fetal growth restriction ...
The new drug application (NDA) (the 'Application') based on the positive results from the pivotal phase III OptiTROP-Lung04 study of sacituzumab tirumotecan (sac-TMT, formerly SKB264/MK-2870) ...
TROPiCS-03 is a basket study designed to evaluate the efficacy and safety of sacituzumab govitecan, a trophoblast cell-surface antigen 2–directed ADC, in patients with metastatic solid tumors.