Total hip replacement is routinely recommended for severe hip osteoarthritis, but data from randomized trials are lacking ...

Weight reduction has been shown to alleviate symptoms of osteoarthritis of the knee, including pain. The effect of glucagon-like peptide-1 receptor agonists on outcomes in knee osteoarthritis ...

Severe tricuspid regurgitation is associated with disabling symptoms and an increased risk of death. Data regarding outcomes after percutaneous transcatheter tricuspid-valve replacement are needed.

Although lead has been mined for 6000 years, lead processing skyrocketed in the 20th century. 1,8 A malleable and durable metal, lead was used to prevent fuel from burning too quickly and to ...

For patients with asymptomatic severe aortic stenosis and preserved left ventricular ejection fraction, current guidelines recommend routine clinical surveillance every 6 to 12 months. Data from ...

Dr. Patrick Malecha (Medicine): A 69-year-old man with a history of myocardial infarction, ischemic cardiomyopathy, and an implantable cardioverter–defibrillator (ICD) was evaluated because of ...

Supported by grants (U01DK072493 and UM1 DK072493, to Dr. Inge, and UM1 DK095710, to Drs. Jenkins and Xie) from the National Institutes of Health (NIH) and grants (UL1TR000077 and UL1TR000114 ...

The heterogeneous clinical presentation of graft microvascular inflammation poses a major challenge to successful kidney transplantation. The effect of microvascular inflammation on allograft ...

On July 24, 2024, a 40-year-old woman (gravida 3, para 1, with a first-trimester pregnancy loss at 24 years of age) began to have fever, chills, generalized myalgia, and severe headache at 30 ...

Patients with IgA nephropathy and severe proteinuria have a high lifetime risk of kidney failure. The efficacy and safety of the selective endothelin type A receptor antagonist atrasentan in ...