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生命科学学院易文/朱强团队揭示糖基化调控肿瘤代谢和免疫逃逸的新 ...
因此,靶向有氧糖酵解选择性杀灭肿瘤细胞的治疗策略成为抗肿瘤药物研发的重要方向。 乙酰葡萄糖胺修饰(O-GlcNAcylation)是近年来发现的一种发生在细胞内蛋白丝氨酸或者苏氨酸残基上的单糖修饰,其失调与肿瘤等人类疾病的发生发展密切相关。研究表明O ...
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