(114,116) After that, the acyl-hydrazide dissociates or gets further deacylated to the free hydrazide, but none of these species show as high potency, selectivity, or τ as the original DFMO.
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Summary: Researchers have discovered that the enzyme ATP-citrate lyase (ACLY) plays a critical role in driving the inflammatory process linked to aging, known as the senescence-associated secretory ...
To address this, Covalys will soon offer a complementary tagging system based on the smaller (∼8 kDa) acyl carrier protein ... be selectively modified with hydrazide- or hydroxylamine ...