药品分类：抗肿瘤药物非小细胞肺癌（NSCLC）是全球范围内常见且治疗难度较大的一种癌症类型。针对这种疾病的治疗，科学家们一直在寻求更有效的治疗方案。氟泽雷塞片（商品名：达伯特），一种革命性的口服靶向药物，专门针对KRAS ...

Scientists have always been fascinated by how our bodies work and how the world around us affects us. Recently, a team from ...

Pacritinib，商品名为Vonjo，是一种用于治疗骨髓纤维化的抗癌药物。它是一种大环蛋白激酶抑制剂。它主要抑制Janus 激酶 2 (JAK2) 和Fms 样酪氨酸激酶 3\CD135 (FLT3)。

After a person quits smoking, an important consideration is how quickly the induction of CYP1A2 dissipates. The primary pharmacokinetic interactions with smoking occur with drugs that are CYP1A2 ...

In general, those with variations affecting the genes – namely CYP1A2 and a gene that regulates it, called AHR – tend to ...

Figure 1 lists the pharmacokinetic drug interactions with smoking. The most clinically significant interactions appear in the shaded rows and are discussed below.

Your healthcare provider may limit your dosage of either medication if you take them together. Avoid taking SNRIs with potent CYP1A2 inhibitors. Taking SNRIs with CYP1A2 substrates may also increase ...

Caffeine's stimulating effects can paradoxically lead to sleepiness due to tolerance, adenosine receptor changes, and individual metabolic differences.

Dr Grimaldi says if you carry the genetic variation CYP1A2 (AA), for example, you will “almost certainly” metabolise caffeine faster than someone who doesn’t, and therefore feel its effects ...

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If you're experiencing occasional sulfur burps, which have a rotten egg smell, there are home remedies and over-the-counter (OTC) products to help get rid of them. Infrequent sulfur burps are ...

Introduction: Inflammatory factors released during severe coronavirus disease-19 (COVID-19) caused by acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are known to influence drug exposure, but ...