Trends in Genetics 22, 46–55 (2006). Argueso, J. L. et al. Double-strand breaks associated with repetitive DNA can reshape the genome. Proceedings of the Naitonal Academy of Sciences 105 ...

A new study in Nature identifies a long-sought cytoplasmic 'sensor' that is responsible, at least in part, for interferon responses induced by double-stranded DNA. How do cells detect non-self ...

Life Sciences Center (LSC) have discovered a unique way for cells to silence specific genes without cutting DNA. This research, led by Prof. Patrick Pausch and published in the journal Nature ...

这项在模式动物秀丽隐杆线虫中进行的研究显示，接触常用的塑化剂邻苯二甲酸苄丁酯（BBP），会导致氧化应激增加和DNA双链断裂增加，进而损害生殖细胞的基因组完整性和染色体分离，导致生殖细胞 功能障碍 。

For additional resources to assist in donor production, contact the core. It is recommended that the investigator request this service once they have a suitable donor DNA ready for microinjection. It ...

They are essential for the survival and reproduction of life on Earth. The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). TComparison of a single-stranded ...

The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA—a single-stranded molecule ...

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

Bacteria frequently encounter adverse environmental conditions, such as nutrient scarcity and antibiotic exposure, which can induce DNA damage ...

Determining the number of copies of a double stranded DNA template (be it genomic DNA, plasmid or an amplified fragment) is essential for many genetic quantification applications in research and ...

A novel discovery in the field of pancreatic cancer treatment has been unveiled, revealing the epigenetic silencing of BEND4 ...

Non-viral alternatives such as linear single-stranded DNA (LssDNA) and circular single-stranded DNA (CssDNA) are emerging as ...