UCLA’s anti-Bredt olefins defy century-old chemistry rule Discovery enables new molecular designs for drug innovation ...

The researchers created several different anti-Bredt olefins by making silyl precursors and then carrying out an elimination ...

UCLA chemists have overturned a century-old rule in organic chemistry that limited molecular design by proving that ...

UCLA chemists have found a big problem with a fundamental rule of organic chemistry that has been around for 100 years — it’s ...

For the first time, chemists have made a class of molecules previously thought too unstable to exist, and used them to ...

UCLA scientists just published a paper in the journal Science that disproves Bredt's rule, which has “constrained chemists ...

According to Bredt's rule, double bonds cannot exist at certain positions on organic molecules if the molecule's geometry deviates too far from what we learn in textbooks. This rule has constrained ...