A: Animal; ACE: Accessory cholera enterotoxin; H: Human; ZOT: Zonula occludens toxin.
The synthetic strategy involves 1,2-cis-L-glucosylation, one-pot glycosylation, and diastereoselective cyclization, providing the cyclo-oligosaccharides in up to half-gram quantities. See Wu et al.
The enzyme responsible for glucosylation (UDP-Glc:glycoprotein glucosyltransferase) appeared to behave as a sensor of glycoprotein conformations as only glucosylates saccharides linked to improperly ...
Common O-GalNAc core structures; Core 1, Core 2 and poly-N-acetyllactosamine structures. N-acetylgalactosamine (GalNAc) can be added to the H-antigen to form the A-antigen. Galactose (Gal) can be ...
Schizophrenia (SCZ) is a severe neuropsychiatric disorder characterized by cognitive, affective, and social dysfunction, resulting in hallucinations, delusions, emotional blunting, and disordered ...