The synthetic strategy involves 1,2-cis-L-glucosylation, one-pot glycosylation, and diastereoselective cyclization, providing the cyclo-oligosaccharides in up to half-gram quantities. See Wu et al.

More information: Ye-Yang Yu et al, Biocatalytic β-glucosylation/ β-galactosylation of Rebaudioside C by glycosynthases, Food Materials Research (2024). DOI: 10.48130/fmr-0023-0043 ...

A: Animal; ACE: Accessory cholera enterotoxin; H: Human; ZOT: Zonula occludens toxin.