免疫系统在一天中的特定时间预测并对抗感染,就像一个尽职尽责的守夜人。最近的研究还发现,免疫细胞的昼夜节律在维持组织完整性和功能方面也发挥着重要作用。例如,在进食期间,特定的免疫细胞会传递代谢信号,优化营养吸收。
Interleukin 2 (IL-2) is the only systemic treatment currently available that is capable of curing patients with metastatic renal cell cancer (RCC). The first indications that IL-2 could mediate ...
The interleukin-6 (IL-6) inhibitors market is poised for significant growth, with a projected compound annual growth rate ...
铁代谢障碍及其改善在慢性肾脏病贫血(以下简称“肾性贫血”)发病和治疗中的重要作用早已被临床医生广泛接受和认可,随着铁代谢的生理及分子学机制被进一步阐明,在临床常规的铁代谢指标之外,铁调素的作用也受到更多关注和重视。金秋十月,中华医学会肾脏病学分会2024年学术年会(CCSN ...
A recent study published in Progress in Neuropsychopharmacology & Biological Psychiatry suggests that cannabidiol (commonly ...
Interleukin-2 (IL-2) is a pluripotent cytokine that regulates the immune system’s response. The IL-2 receptor (IL-2R) is a heterotrimeric protein that binds to IL-2 and reacts to it on the ...
T helper 17 (Th17) cells generate the pro-inflammatory cytokine interleukin-17 (IL17/IL17A). IL17 has been a target for a variety of therapeutic monoclonal antibodies and inhibitors to treat ...
糖尿病是我国常见的慢性疾病,发病率高达12.8%,已构成亟待解决的重大公共卫生挑战。而糖尿病足溃疡(DFU)是一种严重并发症,致病机制错综复杂,在我国的发生率高达8.1%,不仅难以治愈,还伴随着极高的致残率、致死率以及复发率,对患者的身心健康构成了严重威胁。更为严峻的是,DFU的治疗成本高昂,占据了整个糖尿病医疗 ...
A team of bioengineers has developed a mathematical model that clarifies why interleukin-12 (IL-12) -- a potent immune-boosting protein that holds promise for cancer treatment -- loses effectiveness ...