Immunotherapy can remove extracellular amyloid plaques from Alzheimer’s brain, but has so far failed to clear intracellular tau tangles. Now, two papers propose a solution: tagging them for ...

Created using BioRender. In line with VALIDATE objectives, we discuss the challenges shared across these four exemplar complex intracellular pathogens and how synergies may be exploited to achieve ...

The course deals with membrane structure, transport of proteins into the endoplasmic reticulum (ER), through the Golgi apparatus and out of the cell; chemical modification of proteins, different forms ...

Calcium ions play a very important role for triggering the release of insulin from pancreatic beta-cells. The intracellular calcium concentration ([Ca2+]i) is regulated by a tight interplay between a ...

Endocytosis and recycling control the uptake and retrieval of various materials in eukaryotic cells. Mammalian cells have ...

Conventional antibiotics struggle to eliminate intracellular S. aureus due to poor cell penetration. Antimicrobial peptides are a new hope for tackling intracellular bacteria. Accordingly, this study ...

NanoSyrinx has also appointed Dr Edwin Moses as the new chairman of the board of directors. Dr Moses, succeeding Stephen ...

Researchers at the University of Toronto and its hospital partners have developed a method for co-delivering therapeutic RNA ...

This work is published in Cell, in the paper, “Intracellular Ebola Virus nucleocapsid assembly revealed by in situ ...

Calcium (Ca) is a critical macronutrient for all plants, including grapevines. The divalent cation (Ca2+) serves structural roles in cell walls and membranes, is an important counter‐cation for ...