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基于System Xc-/GPX4通路探讨白术内酯I对2型糖尿病大鼠胰岛细胞铁死亡 ...
每日观察大鼠毛发色泽,饮食、饮水及尿量的变化,每周监测FBG 及体质量,根据体质量变化调整给药体积,于0 、4 、8 周测定口服葡萄糖耐量(oral glucose tolerance test ,OGTT )。 给药8 周后,ip 5% 戊巴比妥钠麻醉大鼠,腹主动脉进行采血,离心后取血清冻存。取 ...
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