OBJECTIVE To define the pattern of mRNA expression of all human matrix metalloproteinases (MMPs) described to date in rheumatoid arthritis (RA) and traumatic synovial membrane, in order to ...

Objectives: The role of matrix metalloproteinases (MMPs) in Skin Cutaneous Melanoma (SKCM) development and progression is unclear so far. This comprehensive study delved into the intricate role of ...

An enlarging family of matrix-metalloproteinases has been identified that are calcium-dependent enzymes which specifically degrade collagens and noncollagenous substrates (see [37] for review).

The discovery of new substrates of metalloproteinases within this microenvironment has disclosed a new function in inflammation. The role of these proteases now extends beyond extracellular matrix ...

Researchers explore the mechanisms, therapeutic potential, and clinical applications of curcumin in preventing and treating ...

and lipid peroxydation products), they also produce a set of matrix metalloproteinases (MMPs) that control degradation. MMPs are a family of related zinc-dependent endopeptidases capable of ...

Consuming higher amounts of zinc may significantly increase the risk of endometriosis compared to consuming lower amounts, a new study suggests.

Accumulation of extracellular matrix (ECM) in liver fibrosis is associated with changes in protein abundance and composition depending upon etiology of the underlying liver disease. Current efforts to ...

Here, authors present apical-out nasal organoids using a biochemically defined hydrogel system, revealing that matrix metalloproteinases are required for normal epithelial development.

The study findings suggest that increased dietary zinc is associated with a higher risk of endometriosis. However, further ...

Chemical biology: development of novel molecular probes for DNA sequencing analysis and disease gene discovery Medicinal chemistry: development of new imaging and therapeutic agents towards cancer and ...